As said, for multiplayer games (BF3 etc.) would be the 4core better, but its a piece of old cpu. HD7850 crushes GTX650ti.
Another thing which wasn't mentioned, do you have enough energy to run such a card with this AMD?(3220 takes 55W, 965 takes over 100W i think) - if you would combine it with HD7850, you would have to go with at least 500W (full efficiency at 400W).
I personally went with i3 3220 and HD7770(similar to GTX650ti). I can't comlain at all.