Expanding on what Kitsunestarwind said: according to this thread: http://www.evga.com/forums/tm.aspx?m=1660586&mpage=1&pr...
Some people have been able to get it to "work" - but only by lowering the resolution on the displays to the lowest common denominator. In your case, if your 1080p display can run at 1280x1024, then it should (if the people in the thread speak the truth) work.
BUT: you'll be stretching a 5:4 signal onto a widescreen (16:9) display and it will look nasty as you're not running at its native res. If your 1080p display is physically larger too, that'll mess things up even more as the card will treat the screens as if they are all the same physical size.
So, technically it might "work" - but I'd still agree with the previous posters. It won't "work" in the true sense of the word - it'll look horrible.