I tried to google this, but it was no help. I am wondering if it is possible to set up sli so that each card runs an instance of a game. I want to run two copies of Minecraft on my PC so me and my nephew can play together. I have a dual monitor setup. Minecraft/java doesn't work with sli at all, just one card. I've gotten two instances to work so far by using one card, I set it up so he uses an xbox controller and I use the keyboard and mouse . But is it possible to have it use one card per game?