Can i install a hd 7970 on a Asus M5A78L-M/USB3.0 motherboard?

notea

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yes, definitely, but you will need a powerful CPU so that it doesnt bottleneck the 7970 - such as the FX 8350, with a good PSU to power the GPU, at least a 650W 80+ rated
 

notea

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yep, that'll do just fine .. happy gaming :D

EDIT: if you can afford a 7970, why not go for a better PSU? something like the Corsair TX or HX series, they are better than the CX series