I'm running two MSI GTX 780s twin frozr paired with an i7-4770k and I had massive stuttering-like problems in MetroLL up until just recently. This is what I did and now the game runs flawlessly.
1. Run MetroLL, go into settings and disable vsync in the in-game video settings. Save, quit game.
2. Under Nvidia Control Panel, I went to the game specific settings and set vsync to "use the 3D application setting" but I left triple buffering on.
3. Then go to rivatuner and set your
framerate-limiter to 60.
4. Run game. You will notice the stuttering will be gone, but you'll have massive screen tearing. Go back into the game's in-game options, go to video, then set vsync to "on". (Note: in rivatuner it says to disable vysnc when you have the framerate limiter on so it will function properly, but I've had no problems having both vsync turned on in-game with the framerate limiter set to 60).
This is what I did, and the game runs as smooth as anything I've ever played. I have SSAA set to 2x, since that keeps my temps below 70c. If I set it to 4x, my FPS drop below 60 and my temps skyrocket. Even setting SSAA to "off" is ok because the game still looks amazing. I never uninstalled or reinstalled my game, I didn't remove drivers or update drives. It was that simple fix.