Well, that's the mobo - with this chipset, you'll need a 3rd gen CPU to run 1600, what are you running? If you have a 3rd gen, do you have the latest BIOS? If not, update that. Then if after updating or if you have the current , then reset the CMOS (direction in manual), then try setting DRAM to 1600 manually, set the timings per spec for the sticks, and set the VCCSA to 1.14, then give it a try. If you don't have a 3rd gen you are stuck at 1333, though should be able to tighten the timings down to increase performance i.e. if the sticks are 1600 at 9-9-9-24 or waht ever drop each of the first three timings by 1 i.e. to 8-8-8-24