In your user directory, you can select your document folders => right click => properties => location and move them to your secondary drive.
For your games; when performing the instillation, change the install directory from your C drive to your secondary drive.
If you are using Steam, install Steam directly to the secondary drive and all games should automatically be installed there.
Personally, I would keep the My Games folder on the SSD.
Save game files do not take much space and it may give you a bit of a boost saving/loading your games.