I'm going to get a "MSI N650ti-2GD5/OC BE GeForce GTX 650 Ti BOOST 2GB 192-bit GDDR5 HDCP Ready SLI Support Video Card", and was wondering if there are specifics to matching it to a mobo.
Matching a GPU and mobo isnt really a complicated thing. Almost all Mobo's these days support PCI-E x16 slots which is all you need to run a card like that.