Will any gpu work with any motherboard?

So that question is probably really stupid, but let me clarify. Im not sure if any gpu will work with any motherboard, depending on each product's manufacturer. Basically my question is, will a gpu made by lets say AMD like an HD 7870 work with like an Intel board? Or like more specifically, will a Superclocked GeForce GTX 660 work with my MSI FM2-A75MA-E35 motherboard?
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More about gpu work motherboard
  1. Yes and yes. Plug your GPU into the blue PCIe slot.
  2. Best answer
    As long as the motherboard has a PCI Express ×16 (any color [for other readers]) slot (older mobos don't), and the OS has the drivers installed, any PCIe x 16 GPU should work.

    Some info on PCI Express
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