H100i or equivalent (Cooler Master Seidon, NZXT Kraken)is about the only one big enough to reach 4.5Ghz at a reasonable temperature. $100+
My h80i only gets me to 4.3Ghz at 80C+
Some of the larger air coolers in the 50-70 range will get you there as well. Noctua NDH14, Phanteks PT14PE, Xigmatek Dark Knight or Gaia, Thermaltake Frio.
Have to be careful with the memory as the really big ones will bump into tall sticks. I've also seen a few complaints about the top most PCIe 1x slot not being able to be used.