cpu- Intel Xeon E5-2650
(1119.00)
Mobo-SUPERMICRO MBD-X9DR3-F-O Extended ATX Server Motherboard(dual socket board..apparently works fine with 1 cpu...and upgradeable to 2nd cpu later as money permits^^)
(449.00)
Ram- Kingston 64GB (4 x 16GB) 240-Pin DDR3 SDRAM ECC Registered DDR3 1600 Server Memory DR x4 Model KVR16R11D4K4/64 (can dbl the memory on the single cpu later...and if you add a second cpu can then add 2x 64gb as well on top of that for a total of 256gb...or you can just wait for the 32gb sticks and top out at 512gb with 2x cpu's)
(655.99)
GPU- toss up between k5000(bad render/compute performance but great view port performance) 1600.00, Quadro 6000 ebay for 1000.00(last gen but full compute/view port power and 6gb ram with stable drivers), or the Firepro W8000(mixed reviews..mostly driver related..should be hashed out by now as last posts were over 6months old works great for its price...if the drivers are right) 1429.00. From what I've also read the nvidia cards are only good for pro apps....they are horrid at gaming. On the flip side The W8000 apparently also does gaming as well as pro apps. From a purely multifunction stand point I would lean to the w8000...from a pure pro app pov I would lean to the used quadro 6000...the k5000 seems to only be "ok" for rendering/compute stuff when it is paired with a tesla k20 sep card that runs like 3499.99...I would skip the k5000 personally.
So for the cpu/ram/gpu I suggest it will run you slightly over budget but put you in a very great spot to upgrade later down the road on the cheap(for server/pro world) as prices on that hardware drop. I made the mistake of buying titans x2, i7980x(when it was new), and 24gb non ecc ram thinking it would be great for maya, after effects, etc a couple years back. It is a solid computer, and does gaming amazing......I am finding however it just doesn't stack up to xeon/quadro/firepro/ecc ram when it comes to pro apps.
If I had it to do over I would take the things I suggested above over 2x titans...had 3x580gtx's prior....those programs don't support sli in the gaming sense..and that is where the pro cards shine. My rig is also maxed out on ram, desktop cpu's simply can't compete in the realm of what server cpu's are upgradeable to. Furthermore my cpu is more or less at it's maxed out potential as well...you can't get dual socket desktop cpu motherboards ..they simply aren't designed to work that way. That is where the server cpu's kick it up a notch also...8 cores/16 threads....and then times two....those threads matter once you start rendering your final composited scenes.... minutes v.s hours...believe me it matters when you have to change something and re-render.
As for Hdd's, case, monitor, psu...I would recommend a ssd of >256gb...although in the end it isn't a deal breaker and an easy upgrade. I didn't bother putting any of the aforementioned hardware in the list as I assumed you already had it ready for reformat/repurposing. Anyhow hope that helps...it will be more or less the road map Im taking on my next system
The only thing I'm scared about is I am really new to building a pc, so if there was an issue I'm not sure how to fix it. But if you think the drivers should be better by now it would probably be okay! I do like the idea of a nicer card slightly cheaper than the quadros 
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