I have absolutely no idea about water cooling, I must say you are brave to tackle that on your first build...careful. I turn my PC off every night. It's a waste of not only power but unnecessary usage of components that I think slightly wear down the life. Computers benefit from being turned off.
Yeah, WC on my first build is a big obstacle, But I feel that I've done optimal research and have a pretty good idea on how it's all going to come together without messing anything up.
With prior PC's that weren't custom built, I always shut them off; and I have friends that never shut there PC's off so I was a bit confused. Hopefully someone on here with a water cooling setup and give some advice.