They will work. Some personal issues(you don't have to agree with me)
1) gtx titan is an overpriced gpu. I suggest you to buy gtx 780 and save some money
2) 750 watts will probably struggle with a highly OCed i7, a gtx titan and and a h80
3) if you go for such a high end build, you need a bigger case than 300r, which by the way i am using for my build.