For a system using a single ASUS RADEON R9 280X DirectCU II TOP 3 GB GDDR5 [ R9280X-DC2T-3GD5 ] graphics card a minimum of a 600 Watt or greater system power supply is recommended. The power supply should also have a maximum combined +12 Volt continuous current rating of 37 Amps or greater and have at least one 6-pin and one 8-pin PCI Express supplementary power connectors.
Total Power Supply Wattage is NOT the crucial factor in power supply selection!!!Sufficient Total Combined Continuous Power/Current Available on the +12V Rail(s) rated at 45°C - 50°C ambient temperature, is the most critical factor.
Overclocking of the CPU and/or GPU(s) may require an additional increase to the maximum combined +12 Volt continuous current ratings, recommended above, to meet the increase in power required for the overclock. The additional amount required will depend on the magnitude of the overclock being attempted.
The Corsair VS650 (SKU # 75-001837 / CP-9020051) power supply unit, with its maximum combined +12 Volt continuous current rating of 50 Amps and with two (6+2)-pin PCI Express supplementary power connectors, is more than sufficient to power your system configuration with a single ASUS RADEON R9 280X DirectCU II TOP 3 GB GDDR5 [ R9280X-DC2T-3GD5 ] graphics card.