Two different size monitors and cables

tonyd927

Honorable
Oct 6, 2013
15
0
10,510
Hello,
I have a ASUS 23in IPS HDMI monitor that I am plugging into my graphics card: EVGA GeForce 650ti
and a 19in view sonic LED monitor that I am plugging in using DVI cable.

Can my main monitor, the ASUS, be used at 1080 resolution and the 2nd monitor, the Viewsonic be used at 1440x900 resolution? And will plugging two different monitor sizes and brands do any damage or performance damage to my hardware or software?