The answer is simply no. The following is a review of Hitman: Absolution. The rig uses an Intel Core i7-3960X Extreme Edition (3.30GHz). MSAA is set to 2x and everything else is either set to Ultra or High. There are screenshots of the settings used that you can click on.http://www.techspot.com/review/608-hitman-absolution-performance-benchmarks/
With a GTX 580, the rig was able to get 45 FPS as seen in the below chart. I really doubt setting MSAA to off will give you a 15 FPS boost in performance. Additionally, you do not get any better performance when overclocking the CPU as can be seen in the 2nd chart. With a Radeon HD 7970 and with an i7-3770k clocked from 3.0GHz to 4.5GHz, the increase in performance is only 3 FPS or 1 FPS for every 500MHz.
The last chart basically shows that there is no gain in performance difference between the quad core i7-3770k and the six core i7-3960x.