All depends on the size of the SSD in question.
I have a 128GB Kingston as my primary. OS and all applications on the SSD.
Win 8 Pro, MS Office, Corel, Lightroom, etc, etc, etc.
Takes up about 50GB.
Games live on the HDD.
See this completely self serving tutorial for how and where to put things:http://www.tomshardware.com/faq/id-1834397/ssd-redirecting-static-files.html