You cannot use one large HDD as a partner to several smaller HDD's, each as RAID pairs.
This whole thread results from a very common misunderstanding. RAID1 is NOT an automatic backup system! It fails to protect against many types of failures that a proper backup system does do - like electrical surges, fire, etc. And it does several things that a good backup system would not do - like make sure that EVERY change is in BOTH places, so that you have NO backup before some mistake.
What OP is really looking for is a good backup system. Backing up to a large HDD would make sense, and you might even want to set it up with separate partitions, one for each small HDD that you are backing up. Of course, you will need software to automate the process, and you'll have to decide how often the backups should be done. They really do not need to be instantaneous so that everything is backed up as soon as any change is made.
OP, you should realize, however, that backing things up to another HDD in the same case is NOT a really good backup system. Power surges will threaten all of your components. A fire in the house will damage you backup drive just as much as the others. A virus in any HDD will likely spread to all other units in the system.
You also should consider that a good backup system will have a capacity of two or three times the capacity of the drive being protected. Why? Because you want to keep a sequence of backups over time so that, if you have a problem that actually happened three weeks ago, you have a backup from BEFORE that to rely on. Now, that's why a good system will use both a complete backup and a series of incremental backups over time - you certainly do NOT do full backups every time. But that still requires significant storage space.