If the board you are getting has a PCIe 3.0 x16 slot and, as you said, you have the necessary power and bios, then you probably won't run into issues (short of you getting a card that is too big for your case).
As an example, look at this board, under the expansion slots category. It has the necessary PCIe 3.0 x16 slot and so would probably be fine with just about any gpu card you are likely to buy