Short answer, yes.
Long answer...
Your motherboard supports the following:
Number of Memory Slots: 4×240pin
Memory Standard: DDR3 2133(O.C.)/1866/1600/1333/1066
Maximum Memory Supported: 32GB
Channel Supported: Dual Channel
Your best option is to buy a dual-channel kit of 240-pin ram at 1333 or 1600 mhz.
If you want 4GB, find a 2x2GB kit, you will get better performance with two ram sticks vs. one.