You aren't going to degrade modern computer parts, most of them have expected lifespans >5 years, CPUs have very little that will go wrong with them unless you overvolt them or get them to excessively high temperatures. The first thing to give out on GPUs is usually the fan, but that still comes with a long lifetime on it, there are many systems out there that run 24/7/365 at high load without issue, parts are intended to be able to handle that.
When you start mining just let it run for a while and check on it while your temperatures stabilize, after its been running for an hour your temps should have reached their max. If they are higher than you would like you can look into undervolting your CPU/GPU or look into better cooling solutions for each. Honestly, for the AMD CPU I'd look into a better CPU fan if its going to be running underload because the stock one is pretty whiney when it kicks up to speed.