It depends on what you're hoping for performance-wise. RAID is nice for some applications, and it may give you a bit of a performance enhancement gaming-wise, but there's not a 100% guarantee of that for all games. Plus, in RAID 0 there is no parity (which guards against information loss) so if one drive goes, everything goes.
*EDIT* - I forgot to mention that you should, for any setup but especially with RAID 0, backup your data religiously! Not that RAID setups just blow out all the time but I have SO many customers that put precious business information on their RAID 0s and then take out the drive or lose it or corrupt it.