I am looking at building my own gaming PC, and I was wondering if there is a difference between having a single RAM card and having multiple, smaller cards.
You would be better off with 2 4gb sticks so you can take advantage of dual channel.
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+1 and most of todays CPUs have MCs (memory Controllers) that are native to dual channel with the exception of the socket 2011 CPUs that are native to true quad channel and older X58 where Tri channel was the norm