It completely depends on your settings. You should be able to run at or near the highest quality settings.
If you can't maintain 60FPS most of the time, then do a small amount of tweaking to do so. MULTIPLAYER can drop below 60FPS mainly due to the CPU, however they are still patching both the game on your PC and optimizing the server to improve performance.
There's also some confusing videos which appear to confirm two things though I don't own the game:
1) Windows 8 is working better than W7 for some reason related to the CPU, and
2) Unparking cores (increase min and max CPU usage in Power Options to 100%) increases performance.
Even if this is true, both may be resolved by software patches as it doesn't seem to occur with other games a W7/W8 is normally almost IDENTICAL for game performance.
Hard Drives have no affect on frame rates. They mainly minimize the time to load the game or levels. In a few poorly coded games that access texture data on the drives too frequently, a faster drive can minimize stutter.
Side note:
The stutter in Fallout 3/NV is caused by an improper VSYNC setting which they never fixed. The ONLY good solution is to use the ifpsclamp=60 method which then makes the game run smooth as butter provided you don't drop below 60FPS (not an issue with the setup above). Fallout 3 also requires forcing two cores. Seriously, if you've never played either game get one or if you own a copy, try running around normally and with the fixes below. It's painful how much time I played with the major stutter that was easily fixed (the "stutter fix" at Nexusmods does little compared to this fix and also synchs to 30FPS which is sluggish.)
Simply modify the INI file for each game in its "Documents"->"My Games".. folder (Fallout 3's is "fallout.ini")
Fallout NV:
iFPSclamp=60
Fallout 3:
iNumHWThreads=2
iFPSclamp=60