What OS are you using?
If everything works OK why mess with it? Plus if there is no problems then you are living proof that AMD drivers and Nvidia drivers can exist on the same PC.
I thought about it, but my computer is so slow, I saw a little activity from it and I'd like to not have to have 120 threads running that aren't really doing anything. Only minor problem I've seen is that on launch an annoying pop up from Catalyst alerting that my GPU doesn't work with Catalyst.