Yes!! That mouse is capable of connecting to a unifying receiver. Look on the bottom of the mouse and you may notice this icon
which signifies that the device is capable of connecting to a unifying receiver.
Just plug in the unifying receiver. Open the SetPoint software or Unifying software depending on whichever you use. Click the unifying logo on the left. Click open unifying software if you are in setpoint. You can go through the wizard or do it manually.
Here are detailed instructions on set-up. It's easy, fast, and straight-forward.http://logitech-en-amr.custhelp.com/app/answers/detail/a_id/23116/section/troubleshoot/crid/398/lt_product_id/8086/tabs/1,3,2,4,5/cl/us,en