Going to any solid state drive over a standard mechanical drive is going to offer a very noticeable difference in performance capabilities from Windows startup time, opening and saving files, even loading games. Just be aware that with SSDs there are some optimizations for your system to do to get the best performance and longevity out of it. Fortunately, Samsung (and most all major SSD manufacturers out there now) provides a piece of software to install which not only monitors the SSD health, allows for firmware updates, and performance metrics, but also can easily configure those Windows settings with a single click to optimize your system for an SSD.
Also, I wouldn't recommend running your SSD at more than 80% full because that will not only decrease the performance capabilities but can also decrease the overall life expectancy of your drive.