Will Sapphire Flex AMD Radeon HD 6450 work on my Intel processor?

Sorry if this is dumb, but will the AMD Radeon 6450 work with my Intel Core Duo processor? I am trying to hook up three monitors to my Small Form Factor HP desktop... so options are limited and right before I decided to go with this card, the AMD thing confused me.

Please help! Thanks
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    You can use any manufacturer of graphics with any manufacturer of cpus. So it would work no problem.
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