you can but make sure you have a decent CPU cooler to keep temperatures down. It is a single core CPU and doesn't have a huge OC capability, so keep it at 3.0Ghz, And it shouldn't get too hot to worry about.
Being a single core, even an overclock is not going to help you out much. I used to have one of those semprons, and it sucked, even overclocked. I would recommend updating your bios, then going to ebay and getting an Athlon II X4 or Phenom II X4 from this list.