Can't find a manual for that model, so here's based on a newer model:
https://tcl-django.s3.amazonaws.com/medialibrary/2013/06/IB_E3010_32_39_40.pdf
[Picture] section
* Picture Mode -- "Natural" -- I don't know what this means, but maybe choose "Natural" as that seems like it might have the least processing added
* Brightness -- your choice; won't affect pixel quality
* Contrast -- your choice; won't affect pixel quality (up to a point)
* Saturation -- try to adjust it so colors look rather normal like your monitor
* Sharpness -- 0 -- turn all the way off. I am guessing that 0 means off, but it is possible that 10 may mean off and anything below that means blur the image. (TVs are weird) You want no sharpening added; try 0 to see if that removes it correctly.
* Tint -- try to adjust it so colors look rather normal like your monitor; I don't know what number means normal colors.
* Color Mode -- your choice; this will pick the base color for "white" ... where white will appear redder (warm), neutral, or bluish. Try "Normal" and "Cool"
* Backlight - your choice; won't affect pixel quality
* Dynamic Backlight -- off -- turn off because this will constantly change the screen brightness based on how much of the screen is dark or bright, which is not good for computer use (it means your greyscale levels are always changing and sometimes the change can be annoying if you see it happen). Although, depending on how you use the TV, you might want this on. This will not affect pixel quality as much... so if you like it on for movies or games, then it's probably ok.
* Dyanamic Light Sensor -- off or your choice -- this changes the brightness based on the room; so it changes less than dynamic brightness, but it means your tv is changing greyscale levels yet again.
* Geometry -- (this option might not affect you; I don't know what it's options are, but disable any processing features that would change the pixels; you can list all the options in a reply if you aren't sure.)
* Advanced > Zoom Mode -- don't know what the options are, but you want a 1:1 or no zoom or something like that; This is actually a pretty important setting to get right. If you want to list the options, maybe I can recommend which one, but basically you want the one that does not stretch or distort the signal from the computer to fit the screen in any way; you want it to show pixel for pixel perfect.
* Advanced > 3DNR (Noise Reduction) -- Off -- this could ruin pixel perfect images, mess up antialiasing on text, and cause other issues, if on
* Advanced > Film Mode -- Off -- yet more image processing; might be ok if it is guaranteed to ONLY work if you are playing a video, but it might kick in during other use that you don't want it to, thus, might be better to keep off
If you see any other settings on your model, let me know.
Also, let me add again that you should:
* Use ONLY HDMI
* Run ONLY at 1366x768 resolution.
for this TV to look fairly decent.