montecpa,
Summary Answer > Buy a dual Xeon LGA2011 motherboard from the ASUS Z9PA-D8 series- $360- $535 to be able to add a second processor later. Consider building with a single CPU of 6 or 8 cores and a higher clock speed and adding a second later.
In my view, a system like this to be optimized needs to consider all uses and if possible future applications. For example, if there is any kind of visual work, or high intensity calculation, it may be advisable to have two higher speed 6 or 8-core Xeons than one 10-core. Or, if you buy a dual CPU board, you might build initially with single, faster 6 or 8 core and then add a second one later.
If there is a need or desire for PCIe drives like Ocz Revodrives and/ or future Tesla or Xeon Phi coprocessors, a dual CPU may be desirable so as to add PCIe lanes.
Some questions>
1. Will you be using one Xeon E5-2690 V2 or two?
2. How many VM's do you plan to have loaded at one time?
3. What do you have in mind for file storage?
4. List the applications and uses? Are you doing MATLAB, 3D modeling, or video processing for example?
5. Is there a reason you chose 4 X 16GB for the RAM? Most single CPU server motherboards have 8 slots and good dual Xeon borads have 16 slots. Is your idea to eventually have 128GB or more of RAM?
6. Do you have an overall system budget?
As a conversation starter, follows is a of a kind of generic system- on the level your inquiry suggests. This is more or less a kind of ideal system for my uses, which is heavily image-based- 2D and 3D CAD and rendering. This starts with 2X 4-core Xeon, but with 6 and 8 core as options. My first choice would be to start with a single E5-2687W V2 8-core which is about $50 more than the 10-core E5-2690 V2. The motherboard is the one I would recommend for your use if you have dual CPU's, expensive but high performance, and a lot of desirable features, including having 7X PCIe X16 slots- taking advantage of the extra lanes that dual CPU's provide. I would suggest that you consider building the system on a dual CPU motherboard with the idea to add the second CPU and more RAM later. There are some motherboard options listed below that are in the same series but are less expensive configurations. The choice of Quadro K5000 is to provide a high level of performance for image-based work and of course may be surplus to need. If you are not involved in 3D, I would suggest a Quadro K600. These are very good in 2D (3D is not terrible but not great) and the cost of about $170 will subtract almost $1,000 from the total cost >
BambiBoom PixelCannon Cadamodirendacompilarific ExtremeTurboSignature IWork 9000 ®©$$™®£™©™ _2.7.14
CPU > (2) Xeon E5-2643 V2 Six Core 3.5 / 3.8 GHz LGA2011 25MB > $3146 ($1578 ea)
____
http://www.provantage.com/intel-cm8063501287403~7ITEP3WR.htm
CPU OPT’L > (2) Intel Xeon Processor E5-2637 v2 Four core 3.5 / 3.8 GHz 15M Cache >$1992 ($996 each)
http://ark.intel.com/products/75792/Intel-Xeon-Processor-E5-2637-v2-15M-Cache-3_50-GHz
CPU OPT'L > (2) Intel Xeon E5-2687W v2 Ivy Bridge-EP 3.4/ 4.0GHz 25MB L3 Cache LGA 2011 150W 8-Core Server Processor BX80635E52687V2 $4,400 ($2,200 ea)(this is among the top five most powerful CPU's.
Motherboard > ASUS Z9PE-D8 WS Dual LGA 2011 Intel C602 SATA 6Gb/s USB 3.0 SSI EEB > $534
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http://www.newegg.com/Product/Product.aspx?Item=N82E16813131817
OPT'L > ASUS Z9PE-D16 SSI EEB Server Motherboard Dual LGA 2011 DDR3 1600 > $440
OPT'L> ASUS Z9PA-D8 ATX Server Motherboard Dual LGA 2011 DDR3 1600/1333/1066 > $360
CPU Cooler > CORSAIR Hydro Series H60 (CW-9060007-WW) High Performance Water / Liquid CPU Cooler. 120mm > $130 or $65
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http://www.newegg.com/Product/Product.aspx?Item=N82E16835181030
RAM > 64GB (4) Kingston 1X16GB 240-Pin DDR3 SDRAM ECC Registered DDR3 1866 (PC3 14900) Server Memory Model KVR18R13D4/16 $745 ($185 ea) > VERIFY
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http://www.newegg.com/Product/Product.aspx?Item=N82E16820239756
GPU > NVIDIA Quadro K5000 4GB GDDR5 Graphics card > $1689.
____www.amazon.com/NVIDIA-Quadro-K5000-Graphics-PNY/dp/B009L8E4UO/ref=sr_1_1?ie=UTF8&qid=1391826733&sr=8-1&keywords=quadro+K5000
HD 1 > SAMSUNG 840 Pro Series MZ-7PD512BW 2.5" 512GB SATA III TLC Internal Solid State Drive (SSD) > $400 (OS and Applications)
___
http://www.newegg.com/Product/Product.aspx?Item=N82E16820147194
HD 2 and 3 > (2) Seagate Constellation ES.3 ST2000NM0033 2TB 7200 RPM 128MB Cache SATA 6.0Gb/s 3.5" Enterprise Internal Hard Drive Bare Drive > $ 294 ($197 ea) (RAID 1) (Files, system Image)
___
http://www.newegg.com/Product/Product.aspx?Item=N82E16822178296
Power Supply > CORSAIR HX Series HX850 850W ATX12V 2.3 / EPS12V 2.91 SLI Ready CrossFire Ready 80 PLUS GOLD Certified Modular Active PFC Power Supply > $160.
____http://www.newegg.com/Product/Product.aspx?Item=N82E16817139011
Optical Drive > SAMSUNG DVD Burner 24X DVD+R 8X DVD+RW 8X DVD+R DL 24X DVD-R 6X DVD-RW 16X DVD-ROM 48X CD-R 24X CD-RW 48X CD-ROM SATA Model SH-224DB/BEBE - OEM > $20
Case > Case Labs > Mercury S8 > with options $400
___ http://www.caselabs-store.com/mercury-s8/
OS > Microsoft Windows 7 Ultimate SP1 64-bit- OEM > $190
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http://www.newegg.com/Product/Product.aspx?Item=N82E16832416808
_________________________________________________________
TOTAL = $6,135 or
$4,981 with Xeon E5-2637 V2
Cheers,
BambiBoom
HP z420 (2014) > Xeon E5-1620 quad core @ 3.6 / 3.8GHz > 24GB ECC 1600 RAM > Quadro 4000 (2GB)> Samsung 840 SSD 250GB /Western Digital WD1003FZEX 1TB> M-Audio 192 sound card > AE3000 USB WiFi > HP 2711X, 27" 1920 X 1080 > Windows 7 Ultimate 64 >[Passmark system rating = 3815, 2D= 767 / 3D=2044]
Dell Precision T5400 (2008) > 2X Xeon X5460 quad core @3.16GHz > 16GB ECC 667> Quadro FX 4800 (1.5GB) > WD RE4 500GB / Seagate Barracuda 500GB > M-Audio 2496 Sound Card / Linksys 600N WiFi > Windows 7 Ultimate 64-bit >[Passmark system rating = 1859, 2D= 512 / 3D=1097]
2D, 3D CAD, Image Processing, Rendering, Text > Architecture, industrial design, graphic design, written projects [AutoCad, Revit, 3ds Max, Vray, Solidworks, Sketchup Adobe CS, WordPerfect, MS Office]