is the memory ram pc3-12800 compatible to 1333/1066 mobo?

i was planning to buy a 8gb single stick memory ram pc3-12800 that i found on an online store
but im not sure if this will run to my motherboard pc chips a45g
someone told me it will run on the lower frequency somehow?
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More about memory ram pc3 12800 compatible 1333 1066 mobo
  1. It should run at 1333 on that board.
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