They are supposed to be spaced apart. Slots 1 and 3 should be occupied. You could also do 2 and 4.
Try each stick of RAM separately. One of them may be faulty. Since it is a new motherboard, one of the slots could be faulty also. Try different combinations, such as in slots 1+3, then 2+4, then one stick in all of the slots one after the other.