Just follow the important registry information provided in using the hotfix and I think you'll be good. Best of luck.
Followed it to the letter, and it didn't work (double-checked it 5x too). From what I've been able to find, the reason it's not 'applicable' is because this hotfix was included in SP1. I think it's an issue that is either being caused by McAfee's software itself, or some group policy setting that's telling McAfee to do it this way...but I'm striking out everywhere, so i wouldn't be surprised if I'm wrong on that too. Thanks again!