Few things you need to do here.
You will need to fully re-install Windows clean once you swap out the motherboard, so backup all your stuff or simply buy a new hard-drive to install things on.
You will need the case manual to have all the cord connections for the power, lights and any USB/audio ports, unless they are well labeled.
The motherboard will come with a manual you can follow for that.
And make sure your RAM is compatible or you'll need to buy new ones.
Also make sure your power supply connections match the motherboard, some OEM systems have a modified power connector that won't work with standard motherboards.
Actually putting the thing in the case, not too hard. CPU goes on first before you put it in the case, hard to mess that up but if something does not seem to fit, don't force things. Pop in the CPU, close the cover over it, put a dot of heat grease on it, spread it around to a thin even coating, install the heatsink. Unplug all the cords on your existing motherboard, remove the retaining screws (will probably be around 7-8 of them around the edges and in the middle), move the motherboard out, pop out the existing back pannel from the case.
Look over the new motherboard for where the screw holes are. You may need to move / remove / add standoff screws in the case to match the new motherboard screw holes.
Pop in the new back panel from the new motherboard. CAREFULLY slide the motherboard in over the screw mounts without scraping it, make sure the ports on the back line up to the back panel, screw it in. Then go in and plug the cables in, I'd leave power for last. Put your main drive you will install Windows on on the lowest numbered SATA port. This is where the mobo manual and the case manual go hand in hand to properly connect the power button, reset, lights, fans, front panel USB and audio ports, etc... Install the RAM.
Once all that is in, plug in the power connectors from the power supply, hook up power to the wall, hook up your monitor/keyboard/mouse, cross your fingers and hit the power button. If all goes well you won't hear any beeping or see smoke and you'll see the BIOS screen. If it does not turn on, check the power button cables. Once you see it turn on, shut it down, button up the case again, put in your Windows media, and boot off that to install Windows. Install the drivers once Windows is on there, and activate Windows. Run Windows update, install an anti-virus software, use computer.
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