Would a gtx 650 work with a IPISB-CU carmel2 motherboard? The latest bios update for the motherboard is 2012-02-06 and the card came out 2012-09-13 so I'm not sure if that will be a problem.
Not the exact same GPU but in the end the OP had found info suggesting that mobo is not the highest quality (used other words and I don't want to bash on your PC) and that the mobo would not accept any GPU that it did not come with.
Something to look into and think about before spending the cash on that 650
It mostly will, since both are PCI Express compatible.
GPUs do not always depend on motherboard type, they just need a slot to fit them, a case to hold them and most important a power supply to supply them with enough power.
Not the exact same GPU but in the end the OP had found info suggesting that mobo is not the highest quality (used other words and I don't want to bash on your PC) and that the mobo would not accept any GPU that it did not come with.
Something to look into and think about before spending the cash on that 650