noway sir :
Just wondering; it will affect my future upgrade path
and if they can; how well?
I'll answer it this way.
I have two 780 Ti's in sli, and I can't run ONE 1440p monitor on max settings w/ high AA in Watch_Dogs and get a solid 60 fps.
It just depends on what your expectations are. If you want to run a game at 30 fps on medium settings with no AA, then it could possibly work. However, there is NO graphics card solution that can run 3 1440p monitors in any demanding video game.
If you just want 3 1440p monitors for desktop use? Sure. It would work fine.