Yes, but it won't run it with everything on Ultra. Since the R9-270 is a 2GB card, you'll be locked into the "High" texture setting. (Ultra texture setting requires a 3GB+ video card.) Other graphics details settings will depend on your resolution, but I believe "High" across the board using HBAO+Low and FXAA would be possible. Those are my brother's settings, and he's using a Phenom II X4 & HD7870 @ 1600 x 900.
Why the 1333 RAM, though? Go with 1600: http://uk.pcpartpicker.com/part/crucial-memory-bls8g3d1609es2lx0