So, I wiped my hard drive but now I can't play Fallout New Vegas no more, I don't know why since all my games are running but every time I try to launch the game gives me this error, I searched a lot in many forums and I cant find the answer. And no, I don't need to disable McAfee
It sounds like part of the game was on the drive you wiped.
Yes, its on Steam.
Yes, I verified the local content (and also reinstalled the game).
No, I don't have mods
And the game was installed on driver D, just Steam was installed in the C and all my other games from Steam that are in the same folder with New Vegas in driver D are running, but I always have the problem to run them with error 53, so I have to launch Steam offline mode but that doesnt help it either with Fallout