4 Radeon R9 290Xs in CrossFireX vs 2 Radeon R9 295X2s in CrossFireX?

Which of the two setups would be likely to perform better, 4 290Xs in CFX or 2 295X2s in CFX? Both yield 4 GPUs for the count, have nearly the same clock, TDP, price (per GPU), and memory (per GPU). There's not a single difference I can catch, except that the 295X2 performed slightly lower than the 290X in PassMark (because PM doesn't recognize dual-GPUs). Does anyone have any evidence one way or another?
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More about radeon 290xs crossfirex radeon 295x2s crossfirex
  1. If the memory and clock speeds are the same they should be equal.
  2. 290x "should" be cooler since each gpu has it's own heatsink/fans so that should let them boost a bit more. Not to mention it's cheaper.
  3. Ref 290x quadfire will be less performing than 295x2 CF. But 4 290x watercool will destroy ref 295x2 CF. Watercool both....hmmmmmm I am not sure.
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