You can pretty much game with most any mobo, Asus primarily started the 'Gaming' mobo thing,with improvements aimed at gaming with their ROG series of mobos and are still considered the best, others have followed with 'lines' of 'gaming' mobos and since imitation is the sincerest form of flattery, Asus is still tops, couple years back MSI took a couple of their standard lines of mobos the 45 and 65, and changed the color scheme to red and black imitating the Asus ROG scheme...before them the Rock came out with their Fatal1ty line (again in the Red and Black, and now you have GigaByte changing their Sniper series from Green/Black to, to, to...you guessed it...Red/Black.....I build with Asus, the Rock and GB and still favor the Asus mobos, they alwasys seem to get a little better performance overall then the others, but you can pretty much game on anything....I suggest sticking with the top three Asus, the Rockk and GB...after that you have MSI (poor QC) and then others that generally are lower quality which I stay away from for high end builds.