This happened today.
While in-game there's alot of flickering and white/black stripes. When I exit to desktop the black bar in the middle of the screen serves as a new screen border and theres alot of the before mentioned white/black stripes.
Have considered beating the gpu with a stick, will post results.
Any other suggestions welcomed.
Also, a restart fixes everything for a few minutes after which it comes back with similar results, not as severe if I'm not in-game when it comes back.