I have zyxel powerline adapters, and they don't need any calibration, but I don't know how your tplink ones handle that stuff. Is it hard to calibrate them?
As far as the router part, yes you can do anything with them that you can do with wires
I have a cable modem to router, and then router LAN jack to powerlink, then 3 powerlinks around the house. One even connects to an 8 port switch, which is connected to 5 machines.