See all that stuff under disk activity and processes with disk activity... they all access the drives.
You have quite a bit of add on stuff that use the drives that you might not want starting with the PC; like Raptr (known to scan your drive), GameassistantMain (Could be a trojan), gyazowin....
Start googling each one and turn off ones you only use once in a while (they will usually start when you start the program), get malwarebytes antimalware, update it, then run it from safe mode...