Yes that mobo will be able to run fx 8350, i had mine on it clocked at 4,7ghz with custom vrm cooling, vrm's on it will become an issue if you plan to overclock it , youlll need some cooling on them and they are only 4+1 phases design, but it will definetly handle a stock fx 8350 without issues, and no coller wont change anything much, just make your cpu cooler, and helping to oc cpu