Dual 780ti will be absolutely beast at that resolution, but so would dual 290x's... what I would seriously look at, though, is custom watercooling. Put those cards underwater and all the heat and noise problems go away instantly. You have the budget for it.
@DubbleClick: Why in the world are you telling him to waste money just because he has it? There's absolutely zero reason for games to suddenly start supporting hyperthreading when the average game out there barely supports dual-threading and hyperthreading is an absolute nightmare to support. No game developer is going to say it's worth the man-hours to do that when a fraction of their customer base would have it anyways. That $100 could be way better spent elsewhere. IF he were going to be doing heavy video editing, to the point where it was worth spending $100 to make the renders go by slightly faster, then maybe. He's asking about gaming though.
@ohim: Not. True. Seriously, go research hyperthreading, and then what it takes to support it. The only benefit you get is offloading passive background processes onto the gimp threads, and that's very marginal. Also, games that are single-player only are often more CPU-intense than others, barring 64-player matches of battlefield and heavily-packed instances of MMOs.