A 144 Hz monitor will reduce motion blur, particularly if your system can output more then 60 FPS.
Unfortunately, all 144 Hz monitors have TN panels which have inferior image quality to IPS or PLS panels.
If your computer is producing a higher frame rate than 60 fps and you have a 60 Hz monitor, generally enable vsync.
If you have on one of the very few monitors supporting gsync, then enable this.
Otherwise, unless experiencing tearing, leave vsync disabled.