This is straight off of Nvidias website:
MULTI-MONITOR
How many monitors are supported when running in SLI mode?
With GeForce R180 drivers (or later), standard SLI configurations for 2-way, 3-Way, and quad SLI support a maximum of two monitors. Additional monitors (up to 6 monitors total enabled) may be enabled by using either a motherboard GPU and/or a PhysX capable graphics card (GeForce 8 series or higher with at least 256MB of memory) that does not have the same GPU as those that are SLI enabled.
Can I use SLI multi-monitor in all SLI configurations?
Yes. SLI Multi-monitor is supported in 2-way, 3-way, and Quad SLI configurations and is enabled automatically when SLI technology is enabled in the 'NVIDIA Control Panel' (right-click on your desktop to open).
Can I add a 3rd graphics card in my 2-way SLI enabled PC to connect more monitors?
Yes, you can add an additional graphics card to your PC to connect two additional monitors. The additional graphics card must have a GPU that is different from your SLI GPUs and must be NVIDIA PhysX capable (GeForce 8 series and higher with at least 256MB of memory). For example, two GeForce GTX 2XX GPUs in SLI and a GeForce 9XXX GT is a supported configuration.
Can I run my 3-way SLI configuration as 2-way SLI, connect two monitors, and then use the third graphics card that is not in SLI to connect two additional monitors?
No. A PC containing three graphics cards with the same GPU can only be run in 3-way SLI.
What is the SLI focus display and what does it do?
The SLI focus display allows you to select which monitor will receive the maximum SLI 3D acceleration for full screen 3D applications. In SLI multi-monitor mode, all monitors have 3D acceleration but only one monitor has maximum SLI 3D acceleration.
How do I change the SLI focus display?
The SLI focus display can be configured in three ways: 1) Assigning the primary monitor from the Windows Vista Display Properties Control Panel, 2) assigning the primary monitor from the NVIDIA Control Panel > Set up multiple displays page, or 3) selecting the SLI focus display for the NVIDIA Control Panel > Set SLI configuration page.
Are the SLI visual indicators going to change with SLI multi-monitor enabled?
Yes, the SLI visual indicator will change, but only for the SLI focus display. There will be a small green square that appears to indicate the SLI focus display. It will not change on any other modes or monitors.
Does SLI multi-monitor now support Clone mode?
Yes, clone mode is supported, but the 3D performance on both monitors will be less than the SLI focus display's performance when in Dual View mode.
When you are running a full screen 3D application with the SLI focus display, what happens to the second monitor?
When running a full screen 3D application, the operating system and the application determine what happens to the second screen. The screen may go black or change resolutions to match the primary monitor. In addition, full screen applications prevent you from moving using your mouse and keyboard on the second monitor.
Can I render my 3D game full screen on more than one monitor?
Yes, a 3D game can be rendered full screen on more than one monitor if it is a multi-monitor aware game, such as Flight Simulator X. However, SLI multi-monitor will not let you render standard single monitor applications across multiple monitors.
Does SLI multi-monitor support GeForce 6 and 7 series?
No, currently SLI multi-monitor mode is only available for GeForce 8 series GPUs and above on Windows Vista and Windows 7 operating systems.