I wouldn't.
In my experience, a mod like this will cause a massive performance drop at times on a system like yours causing severe stuttering.
*If you do attempt any mods like this, make a BACKUP of your Skyrim game (easy if using Steam) and write down all the mods you have running.
Then remove, or if necessary reinstall Skyrim completely if you have performance problems. So run with FRAPS at times as well to ensure a solid frame rate (I prefer 60FPS with VSYNC or a minimum of 40FPS with VSYNC OFF).
Other:
I've found most ENB mods to oversaturate the colors. They may look good in videos, but personally I have a collection of subtle mods that i find work best for me. I'll include a list below of my setup which I use with an i7-3770K...