Asus is a good solid motherboard.
16GB is plenty, I have 16GB and except when I was compressing like 80GB of files this one time, I have never used more than 6GB. Games don't make much use of it.
For the one-click OC, I would advise against it. It will raise your power and only give a very small OC. You would get a lot better results by overclocking yourself. Its not hard to learn.